摘要
环氧合酶是参与前列腺素类合成的限速酶 ,其同工酶的发现 ,不仅阐明了一大类非选择性解热镇痛剂的作用本质及产生不良反应的原因 ,而且对新药的开发以及合理的临床用药具有指导意义。综述了环氧合酶同工酶的发现、分布、生理作用 ,在基因水平及蛋白水平的调节 ,在有关疾病中的意义 ,以及环氧合酶同工酶选择性抑制剂的研究现状。
出处
《国外医学（皮肤性病学分册）》
2001年第1期30-33,共4页
Foreign Medical Sciences(Section of Dermatology and Venereology)
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