核素检查在桥本氏甲状腺炎诊断中的应用

To investigate isotope cheking in diagnosing the HT

目的 :为研究核素检查在桥本氏甲状腺炎 (HT)诊断中的应用 ;方法 :以放免法直接检测 2 1例正常人 ,36例HT患者 ,并用伽玛相机进行甲状腺与唾液腺静态显像 ;结果 :HT组患者TT4、FT4低于正常对照组 (P <0 0 5 ) ,促甲状尕激素 (TSH)高于对照组 (P <0 0 5 ) ,抗甲状腺球蛋白抗体 (TGAb)和抗甲状腺微粒体抗体 (TMAb)明显高于对照组 (P <0 0 1 ) ,甲状腺 /单侧唾液腺摄99mTc比值高于对照组 (P <0 0 5 ) ;结论 :HT患者血清TT4、FT4、水平降低 ,TSH、TGAb、TMAb升高 ,且甲状腺 /单侧唾液腺摄99mTc比值升高。故核素检查在HT患者的临床诊断中具有重要价值。

Objective:To investigate isotope cheking in diagnosing the Hashimoto thyroiditis;Methods:21 cases of normal group and 36 HT patients were tested using radioimmunoassay.In the same time they were also scanned with gammar camera on thyroid and salivary;Results:The value of TT 4、FT 4 HT in patients are lower than normal group(P<0 05)while TSH is higher than normal group (P<0 05);TGAb and TMAb are much higher than normal group (P<0 01).The ratio of 99m Tc uptaking between thyroid and single salivary is much higher than normal group (P<0 05);Conclusion:The TT 4、FT 4 level in serum of HT patient are low while the level of TSH TGAb and TMAb are higher.In addition,the ratio of 99m Tc uptaking between thyroid and single salivary is higer,so the isotope checking is very valuable in clinical diagnosing the HT patient. [