以肠梗阻为首发症状的老年人与中青年人大肠癌临床资料比较

Surgical treatment of obstructive colorectal cancer in elderly,middle-aged and young adults

目的比较老年与中青年大肠癌合并梗阻患者的临床、病理特点和外科治疗效果。方法回顾分析我院自2006年3月至2012年7月收治的大肠癌合并急性肠梗阻患者65例的临床资料。结果中青年组患者低分化腺癌比例(28.6%)明显高于老年患者(5.4%),差异有统计学意义(P﹤0.05),Dukes C、D期所占比例也高于老年患者(P﹤0.05)。两组患者术中一般情况与术后并发症及5年生存率无明显差异(P﹥0.05)。结论青年大肠癌患者应该争取早期诊断早期治疗,老年大肠癌患者应尽量争取一期切除才能提高患者的远期生存率,改善生存质量。

Objective Objective： To discuss the clinical and pathological features, and surgical treatment of obstructive colorectal cancer. Methods A retrospective analysis was made on the clinical data of 65 eases of acute obstructive colorec- tal cancer treated in our hospital from March 2006 to July 2012. Results The proportion of poorly differentiated adenocar- cinoma was much higher in young patients than in the elderly, the difference was statistically signiilcant（P 〈 0.05）, as well as the proportion of Dukes C and D（P 〈 0.05）. No significant difference was found between the two groups in general conditions during operation, postoperative complications and five - year survival rate. Conclusions To improve long - term survival and the quality of life, young patients with colorectal cancer should seek early diagnosis and treatment, while the elderly should receive one stage resection as early as possible.