期刊文献+

抗微生物多肽在口腔疾病中的研究进展

Progress of antimicrobial peptides in oral diseases
原文传递
导出
摘要 本文介绍了以防御素家族和cathelicidins家族为代表的抗微生物多肽(antimicrobial peptides,AMPs)的结构、分类和生物学性能及其研究的新进展,并对抗微生物多肽在口腔疾病中的应用研究现状加以综述。抗微生物多肽在口腔医学中的研究和应用尚处于起步阶段,具有较大的发展空间和良好的发展前景。 Defense element family and cathelicidins family as a representative of antimicrobial peptides(AMPs) are introduced including the composition, classification, biological performance and the recent progress. The application status of AMPs in oral disease is also reviewed in this paper. The study and application of AMPs in oral medicine is still in its early stage, and has larger development space and good prospects for development.
作者 王天 李桂红
出处 《武警后勤学院学报(医学版)》 CAS 2014年第1期84-86,共3页 Journal of Logistics University of PAP(Medical Sciences)
关键词 抗微生物多肽 防御素 LL-37 口腔疾病 Antimicrobial peptides Defensin LL-37 Oral disease
  • 相关文献

参考文献1

二级参考文献33

  • 1Blaser MJ. Helicobacter pylori and the pathogenesis of gastroduodenal inflammation. J Infect Dis 1990; 161:626-633.
  • 2Ernst PB, Gold BD. The disease spectrum of Helicobacter pylori:the immunopathogenesis of gastroduodenal ulcer and gastric cancer. Ann Rev Microbiol 2000; 54:615-640.
  • 3Zevering Y, Jacob L, Meyer TF. Naturally acquired human immune responses against Helicobacter pylori and implications for vaccine development. Gut 1999; 45:465-474.
  • 4Shimoyama T, Crabtree JE. Bacterial factors and immune pathogenesis in Helicobacter pylori infection. Gut 1998; 43(Suppl 1): S2-S5.
  • 5Allen LA. The role of the neutrophils and phagocytosis in infection caused by Helicobacter pylori, Curr Opin Infect Dis 2001; 14:273-277.
  • 6Isomoto H, Inoue K, Furusu H, Enjoji A, Fujimoto C,Yamakawa M, Hirakata Y, Omagari K, Mizuta Y, Murase K,Shimada S, Murata I, Kohno S. High-dose rabeprazole/amoxicillin vs rabeprazole/amoxicillin/metronidazole as second-line treatment after failure of the Japanese standard regimen for Helicobacter pylori infection. Aliment Pharmacol Ther 2003; 18:101-107.
  • 7van Wetering S, Sterk PJ, Rabe KF, Hiemstra PS. Defensins:Key players or bystanders in infection, injury, and repair in the lung. J Allergy Clin Immunol 1999; 104:1131-1138.
  • 8Chertov O, Yang D, Howard OMZ, Oppenheim JJ. Leukocyte granule proteins mobilize innate host defenses and adaptive immune responses. Immunol Rev 2000; 177:68-78.
  • 9Bals R. Epithelial antimicrobial peptides in host defensea gainst infection. Respir Res 2000; 1:141-150.
  • 10Harder J, Bartels J, Christophers E, Schroder JM. Isolation and characterization of human beta -defensin-3, a novel human inducible peptide antibiotic. J Biol Chem 2001; 276: 5707-5713.

共引文献9

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部