有机相中脂肪酶催化拆分环氧丙醇的研究

Studies on Resolution of Glycidol Catalyzed by Lipase in Organic Media

用正交实验方法筛选出有机相中酶促拆分环氧丙醇反应的最适酶源为猪胰脂肪酶(PPL ) .考察溶剂、酰基供体和加酶量对反应的影响 。

The optimal enzyme resource, porcine pancreatic lipase(PPL), was confirmed by proper test in the resolution of racemic glycidol via esterification with a fatty acid in organic media. The effects of organic solvents, acyl donors and amounts of lipase on the reaction were studied.