100kVp条件下头颈CTA检查中碘克沙醇(270mgI/mL)个性化注射方案的成像效果初探

Study of image quality of head and neck CT angiography with 100kVp technique:individualization protocol of Iodixanol (270mg I/mL)administration

目的：探讨100kVp条件下、头颈部CTA检查中碘克沙醇（270mgI／mL）个性化注射方案的成像效果。方法：连续50例患者行头颈部CTA检查。使用对比剂碘克沙醇（270mgI／mL），个性化对比剂注射方案如下：注射总量一体重（kg）×0．5mL／kg；根据注射时间的不同（分别为7、8和9s）将患者分为3组（4g次为A、B、C组）；注射流率一注意总量／注射时间，规定最高流率为6mL／s；采用对比剂智能跟踪触发技术，兴趣区置于主动脉弓处，阈值为80HU。由两位阅片者对3组的重组图像进行主观评估（5分法），并测量颈部及脑内动脉的CT值。结果：三组患者的年龄、性别、身体质量指数（BMI）的差异无统计学意义（P〉0．05）。三组图像的主观评分分别为4．75±0．41、4．85±0．34和4．29±0．61，A组与B组主观评分的差异无统计学意义（P〉0．05），A组、B组与C组间主观评分的差异有统计学差异（P=0．004、0．024）。三组图像上颈动脉及脑内动脉的CT值：A组与B组间CT值的差异无统计学意义（P〉0．05），A组、B组与C组间CT值的差异有统计学差异（P=0．001～0．037）。结论：碘克沙醇（270mgI／mL）在头颈CTA检查中可进行个性化注射，图像质量可满足诊断需求。

Objective：To evaluate the feasibility of head and neck CTA with 100kVp technique and individualization protocol of Iodixanol （270 mg I/mL） administration. Methods： 50 patients underwent head and neck CTA using Iodixanol （270mg I/mL） as contrast medium. The individual contrast medium protocol were as follows： total volume of contrast medium administrated： weight（kg） × 0.5mL/kg. According to different time period of injection, which were 7s, 8s and 9s, these patients were divided into 3 groups （Group A,Group B, Group C respectively）;the injection rate： volume/injection time,with the highest rate as 6mL/s. Using smart tracing trigger technique for contrast injection, the region of interest （ROD was placed at aortic arch,the threshold was set as 80HU. The reformatted images were subjectively evaluated by 2 radiologists with 5 scale method, and the CT values of carotid artery and intra-cerebral artery were measured. Results： There were no significant statistic differences in gender, age and BMI among the 3 groups （P〉0.05）. The image quality scores of Group A,Group B and Group C was 4. 75±0.41,4.85±0.34 and 4.29±0.61 respectively,no statistic difference was existed between Group A and Group B （P〉0.05） ,significant statistic difference was existed between Group A,Group B and Group C （P=0. 004 and 0. 024 respectively）. Of the CT values of carotid arteries and intra-cerebral arteries of the 3 groups, no statistic difference was showed between Group A and Group B （P〉0.05）, yet there were significant differences between Group A,Group B and Group C （P=0. 001 and 0. 037 respectively）. Conclusion： Individualization of injection pro- tocol is feasible in head and neck CTA with iodixanol （270mg I/miL）. The image quality can meet the requirement of diagnosis.