剖宫产手术预防用抗菌药物856例的临床分析

Clinical analysis on the prophylactic use of antibiotics during perioperative period of cesarean section: 856 cases

目的 了解医院剖宫产围手术期预防用抗菌药物的现状,为医院临床合理用药提供依据.方法 对该院2012年1～12月856例剖宫产围手术期预防应用抗菌药物情况进行回顾性分析.结果 856例剖宫产围手术期100％应用了抗菌药物;药物以头孢替安、头孢西丁为主,联合用药214例（75.00％）,用药持续时间≥72h者526例,≤48h者25例,≤24h者305例;766例为断脐后给药,未发生手术部位感染者.结论 医院剖宫产围手术期预防用抗菌药物基本合理,但仍存在抗菌药物选择不合理及使用时间过长等,应进一步加强管理.

Objective To investigate the current situation of prophylactic use of antibiotics during perioperative peri- od of cesarean section in our hospital to provide basis for clinical rational drug use. Methods From January to December in 2012,856 patients who were administrated prophylactic antibiotics during perioperative period of cesarean section in our hospi- tal were analyzed retrospectively. Results During perioperative period of cesarean section, all 856 patients were administrated prophylactic antibiotics, most of which were cefotiam and cefoxitin. Combined medications were used in 214 cases. Duration of drug use was no less than 72 hours in 526 cases, no more than 48 hours in 25 cases, and no more than 24 hours in 305 cases. In 766 patients, antibiotics were administrated after omphalotomy,with no surgical site infection. Conclusion Prophylactic use of antibiotics during perioperative period of cesarean section in our hospital is basically reasonable. However, there are some problems such as unreasonable choice of antibiotics, too much time of antibiotics use, etc. Therefore, management of using anti- biotics should be further strenathened.