摘要
酒精性脂肪肝(alcoholic fatty liver disease,AFLD)是过量饮酒引起的肝细胞损伤性疾病,表现为渐进性的肝脏脂肪变性、肝炎和肝硬化。目前我国人民的生活水平不断增高,酒类产品的消耗量也逐年递增,从而导致人群中酒精性脂肪肝病的发病率明显上升。本文就我国酒精性脂肪肝病的流行状况、易感因素、发病机制和预防治疗等方面作一概述,并对瘦素(leptin)在酒精性脂肪肝病治疗中的作用进行展望。
Alcoholic fatty liver （AFLD） is the liver cell injury disease induced by excessive drinking, manifested as progressive fatty degeneration of the liver, hepatitis and cirrhosis. Along with the promotion of our economic level, the consumption of alcohol beverage has been increased in China, making the incidence of AFLD rising in China. Here we review the epidemiology, predisposing factors, pathogenesis, prevention and treatment of AFLD and show the prospective utilization of leptin in AFLD therapy.
出处
《胃肠病学和肝病学杂志》
CAS
2014年第4期376-379,共4页
Chinese Journal of Gastroenterology and Hepatology
关键词
酒精性脂肪肝
流行病学
易感因素
发病机制
防治
瘦素
Alcoholic fatty liver disease （AFLD）
Epidemiology
Predisposing factors
Pathogenesis
Preventionand treatment
Leptin
