摘要
系统性红斑狼疮(SLE)是自身免疫介导的,以免疫性炎症为突出表现的结缔组织病。血清中出现以抗核抗体为代表的多种自身抗体和多系统累及是SLE的两个主要临床特征。几乎各种自身免疫性疾病的临床表现均有可能发生在SLE。原发性胆汁性肝硬化(PBC)是慢性进行性胆汁淤积性肝脏疾病,临床有瘙痒、黄疸、肝肿大等表现,绝大多数患者抗线粒体抗体阳性。
Systemic lupus erythematosus (SLE) is a connective tissue disease which is an autoimmune disease as well. It' s mediated by autoimmunity and the autoimmune inflammation is the specialty. The two clinical characteristics are antibody to nuclear antigen in serum and many systems are involved. Almost every autoimmune disease may associate with SLE. Primary biliary cirrhosis ( PBC ) is irritation and swelling of the bile ducts of the liver, which blocks the flow of bile. Itching, jaundice and enlarged liver are most common clinical symptoms. Antimitochondrial antibodies are detected in most cases.
出处
《胃肠病学和肝病学杂志》
CAS
2014年第4期401-401,405,共2页
Chinese Journal of Gastroenterology and Hepatology