1Nose K,Shibanuma M,Kikuchi K,Kageyama H,Sakiyama S,Kuroki T.Transcriptional activation of early-response genes by hydrogen peroxide in a mouse osteoblastic cell lineEuropean Journal of Biochemistry,1991.
2Ihara Y,Toyokuni S,Uchida K,et al.Hyperglycemia causes oxidative stress in pancreatic beta-cells of GK rats, a model of type 2 diabetes. Diabetes . 1999
3Ohlsson H,Karlsson K,Edlund T.IPF1, a homeodomain-containing transactivator of the insulin gene. EMBO Journal . 1993
4Evans JL,Goldfine ID,Maddux BA,Grodsky GM.Are oxidative stress-activated signaling pathways mediators of insulin resistance and beta-cell dysfunction?. Diabetes . 2003
5Satoshi Kawashima,Taka-aki Matsuoka,Hideaki Kaneto,Yoshihiro Tochino,Ken Kato,Kaoru Yamamoto,Tsunehiko Yamamoto,Munehide Matsuhisa,Iichiro Shimomura.Effect of alogliptin, pioglitazone and glargine on pancreatic β-cells in diabetic db/db mice[J]. Biochemical and Biophysical Research Communications . 2010 (1)
6H. Wang,T. Brun,K. Kataoka,A. J. Sharma,C. B. Wollheim.MAFA controls genes implicated in insulin biosynthesis and secretion[J]. Diabetologia . 2007 (2)
7Domenico Accili,Karen C Arden.FoxOs at the Crossroads of Cellular Metabolism, Differentiation, and Transformation[J]. Cell . 2004 (4)
8Koji Sakai,Kazuya Matsumoto,Takeshi Nishikawa,Mihoshi Suefuji,Kazuhiko Nakamaru,Yoshiaki Hirashima,Junji Kawashima,Tetsuya Shirotani,Kenshi Ichinose,Michael Brownlee,Eiichi Araki.Mitochondrial reactive oxygen species reduce insulin secretion by pancreatic β-cells[J]. Biochemical and Biophysical Research Communications . 2003 (1)
9Shin-ichi Gorogawa,Yoshitaka Kajimoto,Yutaka Umayahara,Hideaki Kaneto,Hirotaka Watada,Akio Kuroda,Dan Kawamori,Tetsuyuki Yasuda,Munehide Matsuhisa,Yoshimitsu Yamasaki,Masatsugu Hori.Probucol preserves pancreatic β-cell function through reduction of oxidative stress in type 2 diabetes[J]. Diabetes Research and Clinical Practice . 2002 (1)
10Kataoka, Kohsuke,Han, Song-iee,Shioda, Setsuko,Hirai, Momoki,Nishizawa, Makoto,Handa, Hiroshi.MafA is a glucose-regulated and pancreatic β-cell-specific transcriptional activator for the insulin gene. Journal of Biological Chemistry . 2002
5Abdul-Ghani MA, Williams K, DeFronzo RA, et al.What is the best predictor of future type 2 diabetes [J]? Diabetes Care, 2007,30(8) : 1544-1548.
6Poitou V, Amyot J, Semache M, et al.Glucolipotoxicity of the pancreatic beta cell [ J ].Biochim Biophys Acta, 2010,1801 ( 3 ) : 289-298.
7Tenenbauma H, Behar S, Boyko V, et al.Long-term effect of bezafibrate on pancreatic beta-cell function and insulin resistance in patients with diabetes [ J ].Atherosclerosis, 2006,13 (8):7-18.
8Lalloyer F, Vandewalle B, Percevault F, et al.Peroxisome proliferator-activated receptor-a improves pancreatic adaptation to insulin resistance in obese mice and reduce lipotoxicity in human islets [ J ] .Diabetes, 2006,55 ( 8 ) : 1605-1613.
9Gfike B. Islet cell function: alpha and beta cell-partners towards normoglycacmia [J]. Int J Clin Pract Suppl,2008, (159) :2-7.
10Scirica BM, Bhatt DL, Braunwald E, et al. Saxagliptin and cardi- ovascular outcomes in type 2 diabetes mellitus[ J]. N Engl J Med, 2013,369 (14) : 1317-1326.
