BMI、血糖及血钙水平与急性胰腺炎病情严重程度的相关性

Relationship of body mass index, blood glucose, and blood calcium with severity of acute pancreatitis

目的探究BMI、血糖及血钙水平与急性胰腺炎患者病情严重程度的相关性。方法选取2012年6月至2013年6月于本院就诊的62例急性胰腺炎患者，按照病情严重程度，分为重症急性胰腺炎组（SAP组）10例，轻症急性胰腺炎组（MAP组）52例，对比两组患者的BMI、血糖及血钙水平，并行相关性分析。结果SAP组的BMI、血糖及血钙水平与MAP组相比，差异均具有统计学意义（P〈0．05）；Ranson评分〈3、CT严重度指数〈3、BahhazarCT分级为A／B／C级的BMI、血糖及血钙水平，分别与Ranson评分≥3、CT严重度指数≥3、BalthazarCT分级为D／E级相比，差异具有统计学意义（P〈0．05）；Ranson评分、CT严重度指数及BalthazarCT分级与BMI、血糖、血钙，均呈明显相关（P〈0．05）。结论急性胰腺炎患者病情严重程度与BMI、血糖及血钙水平明显相关，可以作为评估该类患者病情发展及预后的指标。

Objective To investigate the relationship of body mass index （ BMI）, blood glucose, and blood calcium with se- verity of acute pancreatitis. Methods A total of 127 cases of patients with acute pancreatitis was divided into 10 cases of severe acute pancreatitis group （SAP group）, and 52 cases of mild acute pancreatitis group （MAP group）, according to the severity. BMI, levels of blood sugar and blood calcium of two groups were compared, respectively. Correlation analysis was carried out among those parame- ters. Results The differences in BMI, blood sugar, and blood calcium between SAP and MAP groups were statistically significant, respectively （ P 〈0. 05）. The differences in BMI, blood sugar, and blood calcium between patients [Ranson score〉3, Balthazar computed tomography（CT） grade D or E, and computed tomography severity index （CTSI） I〉 3 ） ] and patients [ Ranson score 〈 3, Balthazar CT grade A, B, or C, and CTSI 〈 3 （ P 〈 0.05） ] were statistically significant （ P 〈 0. 05）, respectively. Pearson correla- tion coefficient analysis showed significantly positive correlations among BMI, blood glucose, blood calcium, Ranson score, Balthazar CT grade, and CTSI （ P 〈 0. 05）. Conclusions Severity of acute pancreatitis patients was related to BMI, blood sugar, and blood calcium. All of them can be used as evaluation index of disease progression and prognosis in patients.