钛材料在人工唾液中抗腐蚀性能的体外研究

Corrosion Resistance of Titanium Material in the Artificial Saliva: an In Vitro Study

目的了解钛材料在人工唾液中的抗腐蚀性,为临床选择合适的口腔修复材料提供实验依据和理论基础。方法选择钛材料,配制不同pH值的人工唾液分别为2.0、3.0、5.0、7.4,检测钛材料在不同人工唾液中24、48、72h钛离子的析出量;此外,检测钛材料与镍不同接触面积对钛离子析出量的影响。结果钛离子的析出量pH 2.0>pH 3.0>pH 5.0>pH 7.4,而钛离子析出量在浸泡时间72h>48h>24h,pH值为2.0、3.0、5.0时差异有统计学意义(P<0.05);而pH值7.4条件下不同时间点的钛离子析出量差异无统计学意义(P>0.05)。此外,钛与异种金属镍接触面积50mm2相比较,钛镍接触面积100mm2的钛离子析出量较大,差异有统计学意义(P<0.05)。结论酸性环境可加速钛离子析出量,影响钛材料的抗腐蚀性。镍钛结合面积的增加会加速钛离子的析出,建议镍过敏的患者慎用钛镍口腔修复材料。

Objective To provide the experimental and theoretical basis for clinical choosing appropriate orthodontic repair materials,we studied the corrosion resistance of titanium material in artificial saliva.Methods We chose titanium material,prepared different pH artificial saliva such as 2.0,3.0,5.0 and 7.4,and detected titanium ion precipitation amount from titanium material in different artificial saliva with 24h,48h and 72h.In addition,we detected the effect of material different contact area between nickel and titanium on the quantity of titanium ion precipitation.Results Titanium ion precipitation amount of pH 2.0 was larger than these of pH 3.0,pH 5.0 and pH 7.4.While in pH 2.0,3.0 and 5.0 titanium ion precipitation amount in the soaking time 72h was larger than these of 24h and 48h （P ＜0.05）.Under the condition of different time point,titanium ion precipitation had no statistical significance in pH 7.4 （P ＞0.05）.In addition,compared with contact area 50mm2,titanium nickel titanium ion precipitation amount of contact area 100mm2 was larger （P ＜ 0.05）.Conclusion Acid environment can accelerate the titanium ion precipitation amount and affects corrosion resistance of titanium materials.Increase of combined area between nickel and titanium can accelerate titanium ion precipitation,therefore,it is suggested that it should be caution to choose nickel titanium nickel orthodontic restorative materials in patients with allergic to nickel.