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嗅黏膜间充质干细胞在神经修复中的研究进展 被引量：3

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摘要 嗅黏膜间充质干细胞(olfactory mucosa mesenchymal stem cells,OM-MSCs)是一类存在于嗅黏膜的多分化潜能的干细胞,在一定的体外条件下可分化为成骨细胞、脂肪细胞、平滑肌肌细胞、神经细胞等,且易于取材,可自体移植,无免疫排斥反应,无伦理道德问题,为神经系统疾病治疗提供了新的细胞来源,可在神经修复和功能重建中发挥治疗作用。
作者 葛丽特 卢明
机构地区 湖南师范大学第二附属医院 解放军
出处 《国际神经病学神经外科学杂志》 2014年第1期66-69,共4页 Journal of International Neurology and Neurosurgery
基金 国家自然科学基金(编号:81371358) 湖南省自然科学基金项目(14JJ2060) 湖南省教育厅湖南省高校科研项目(编号:12C0238) 湖南省研究生创新项目(编号:CX20121230)
关键词 嗅黏膜 间充质干细胞 生物学特性 细胞移植
分类号 R329 [医药卫生—人体解剖和组织胚胎学]
  • 相关文献

参考文献28

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二级参考文献28

  • 1唐洲平,王萍,康慧聪,雷霆,朱遂强,王伟,方思羽.嗅鞘细胞对神经干细胞增殖分化的影响[J].中华实验外科杂志,2005,22(9):1123-1124. 被引量：12
  • 2袁源,杨树源,韩忠朝,张晓辉.人脐带间充质干细胞体外扩增和向神经元样细胞定向诱导分化的研究[J].中华神经医学杂志,2006,5(3):230-236. 被引量：29
  • 3Fu YS Cheng YC Lin MY Cheng H Chu PM Chou SC Shih YH Ko MH Sung MS.Conversion of human umbilical cord mesenchymal stem cells in Wharton＇s jelly to dopaminergic neurons in vitro： potential therapeutic application for Parkinsonism[J].中国生物学文摘,2006,20(10):22-23. 被引量：140
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  • 6Li Y, Carlstedt T, Berthold CH, et al. Interaction of transplanted olfactory-ensheathing cells and host astrocytic processes provides a bridge for axons to regenerate across the dorsal root entry zone. Exp Neurol ,2004,188 (22) :300-308.
  • 7Ramer LM , Au E, Richter M W , et al. Peripheral olfactory ensheathing cells reduce scar and cavity formation and promote regeneration after spinal cord injury. J Comp Neurol, 2004, 473(1):1-15.
  • 8Shukla S, Chaturvedi R, Roy N et al. Enhanced survival and function of neural stem cells-derived dopaminergic neurons under influence of olfactory ensheathing cells in parkinsonian rats. J Neurochem, 2009,109(2) :436-451.
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共引文献2

同被引文献15

  • 1葛丽特,卓毅,段答,赵振宇,滕晓华,王磊,卢明.人嗅黏膜间充质干细胞的生物学特性[J].中南大学学报（医学版）,2015,40(1):53-58. 被引量：11
  • 2Bradley J. Goldstein,Joshua M. Hare,Seth Lieberman,Roy Casiano.Adult human nasal mesenchymal stem cells have an unexpected broad anatomic distribution[J]. International Forum of Allergy and Rhinology . 2013 (7)
  • 3W Murrell,F Fe?ron,A Wetzig,N Cameron,K Splatt,B Bellette,J Bianco,C Perry,G Lee,A Mackay-Sim.Multipotent stem cells from adult olfactory mucosa. Developmental dynamics : an official publication of the American Association of Anatomists . 2005
  • 4Hwang SH,Park SH,Choi J,et al.Age-related characteristics of multipotent human nasal inferior turbinate-derived mesenchymal stem cells. PLo S One . 2013
  • 5Hwang SH,Park SH,Choi J,et al.Characteristics of mesenchymal stem cells originating from the bilateral inferior turbinate in humans with nasal septal deviation. PLo S One . 2014
  • 6Wolfgang Wagner,Frederik Wein,Anja Seckinger,Maria Frankhauser,Ute Wirkner,Ulf Krause,Jonathon Blake,Christian Schwager,Volker Eckstein,Wilhelm Ansorge,Anthony D. Ho.Comparative characteristics of mesenchymal stem cells from human bone marrow, adipose tissue, and umbilical cord blood[J]. Experimental Hematology . 2005 (11)
  • 7Woodbury D,Schwarz EJ,Prockop DJ,et al.Adult rat and human marrow stromal cells differentiate into neurons. Journal of Neuroscience Research . 2000
  • 8Jian-an WANG,Tie-long CHEN,Jun JIANG,Heng SHI,Chun GUI,Rong-hua LUO,Xiao-jie XIE,Mei-xiang XIANG,Xing ZHANG.Hypoxic preconditioning attenuates hypoxia/reoxygenation-induced apoptosis in mesenchymal stem cells[J].Acta Pharmacologica Sinica,2008,29(1):74-82. 被引量：25
  • 9黄秋生,陆汉强,周月鹏,贺清华,孙湘兰,姜平,张志坚.成人鼻黏膜间充质干细胞的体外培养和多向诱导分化[J].临床耳鼻咽喉头颈外科杂志,2012,26(11):490-493. 被引量：9
  • 10王磊,段答,赵振宇,滕晓华,刘波,葛丽特,卢明.嗅鞘细胞无血清上清液诱导C17.2神经干细胞定向分化及分化后细胞活力检测[J].中国修复重建外科杂志,2014,28(5):633-638. 被引量：1

引证文献3

二级引证文献3

国际神经病学神经外科学杂志
2014年 第1期

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