氨基磺酸和尿囊素的合成研究

Study On the Synthesis Of Aminosulfonic Acid and Allantoin

用常规加热和微波加热两种方法合成了尿素的两种深加工产品—氨基磺酸和尿囊素。氨基磺酸的合成是用尿素和发烟硫酸反应 ;尿囊素的合成是用硝酸氧化乙二醛溶液制得乙醛酸后 ,再加入氢氧化钙和氯化钙 ,使乙醛酸以钙盐形式析出 ,然后在盐酸介质中与尿素缩合而成。微波合成具有快速和简便等优点。

In this paper, aminosulfonic acid and allantoin are respectively synthesized by microwave irradiation and conventional heating. Carbamide reacting with H 2SO 4 forms aminosulfonic acid. Allantoin is prepared by oxidation of the aqueous solution of glyoxal into glyoxylic acid which is then used to synthesize allantoin. The results show that the synthesis with microwave irradiation is both quick and convenient.