中医药治疗非小细胞肺癌研究简况

Traditional Chinese Medicine Treatment of Non-small Cell Lung Cancer Research

非小细胞肺癌为本虚标实之证,环境污染、烟毒等因素可提高发生率;辨证分型结合现代医学治疗成为主导思想,在增效减毒、提高生存质量、延长生存期、改善免疫状态和抗术后复发转移等方面疗效显著。对于不易手术、放化疗患者和晚期体质较弱的患者更为适用,但缺乏循证医学支持,临床疗效评价标准不规范,符合多中心、随机化及大样本研究规范的少,结果可靠度不高,未来期待统一规范辨证分型、临床疗效评价标准、规范研究设计。

Non-small cell lung cancer is a syndrome of deficiency in origin and excess in superficiality. The environmental pollution, poisonous smoke and other factors could increase the occurrence of NSCLC. As a dominant treatment philosophy, the combination of syndrome differentiation and modern medicine has obvious curative effects in synergism and attenuation, improving the survival quality, prolonging the survival period, improving the immune state, Anti-metastasis, anti-relapse after surgical operation, and other aspects. This method is more suitable for the patients who could not be treated with surgical operation, those who are treated with radiotherapy and chemotherapy, and end-stage and weak patients. However, by the lack of evidence- based medical support, the evaluation standards for clinical curative effects are not standardized, only few are consistent with the multi-center, random and large-sample research criterion, and the results have a low reliability. We hope the unified regulations for syndrome differentiation and the evaluation criterion and standard design for clinical curative effects will be addressed in future studies.