大脑中动脉深穿支供血区单发梗死病灶大小临床意义

CLINICAL SIGNIFICANCE OF THE SIZE OF SINGLE INFARCTION IN THE BLOOD-SUPPLY AREA OF MIDDLE CEREBRAL ARTERY PERFORATING ARTERIES

目的探讨大脑中动脉(MCA)深穿支供血区单发梗死病灶大小与MCA狭窄及脑白质病变的相关性。方法选择住院急性脑梗死病人44例,完善颅脑磁共振(MRI)平扫、颅内血管及相关辅助检查,根据MRI T2相上MCA深穿支分布区单发梗死病灶大小分为腔隙性脑梗死(LI,≤15mm)组19例和非腔隙性脑梗死(NLI,>15mm)组25例,比较两组的一般临床资料及相对应的MCA狭窄和脑白质疏松者所占的比例。结果 LI组年龄和糖尿病病人所占比例高于NLI组,差异有显著性(t=2.640,χ2=5.775,P<0.05);两组MCA狭窄者及脑白质疏松者的比例差异无显著性(P>0.05)。结论 MCA深穿支分布区单发梗死灶的体积与MCA狭窄及白质疏松无明显相关。

Objective To study the relationship between the size of single infarct in the blood-supply area of middle cerebral artery （MCA） perforating arteries and the stenosis of MCA as well as leukodystrophy. Methods Forty-four inpatients with acute cerebral infarction were selected and brain MRI, MRA and other related examinations carried out. According to the size of the infarcts, which were divided into lacunar infarction （LI, ≤15 mm, 19 cases） and non-lacunar infarction（NLI, 〉15 mm, 25 cases）. A comparison was made between the two groups in terms of clinical data, corresponding MCA stenosis and the ratio of leukoareosis. Results In the LI group, the ratio of advanced age and diabetes were higher than NLI group, the difference being significant between the two groups （t=2.640,χ2=5.775,P〈0.05）. The ratio between the two groups were not significantly different in regard to stenosis of MCA and leukoareosis （P〉0.05）. Conclusion No obvious correlation was found between the size of the single infarction and both MCA stricture and leukoareosis.