4103例泌尿生殖道支原体感染及药敏分析

Detection and drug sensitivity of mycoplasma in 4103 cases of urogenita infection

目的通过分析泌尿生殖道支原体感染及药敏情况,为临床提供用药指导。方法采用支原体检测试剂盒进行支原体属培养和药敏试验。结果 4 103例患者标本中,检出支原体属1 336株,总阳性率为32.56%;其中单一解脲脲原体(Uu)感染1 227例,阳性率为91.84%;单纯人型支原体(Mh)感染15例,阳性率为1.12%;Uu+Mh混合合感染94例,阳性率为7.04%。解脲脲原体对阿奇霉素、红霉素、交沙霉素、罗红霉素、米诺环素、强力霉素敏感性高;单纯人型支原体对交沙霉素、米诺环素、强力霉素敏感。结论泌尿生殖道支原体感染以Uu为主。支原体大多具有多重耐药性,临床治疗需根据药敏结果选药物。

Objective To analyze mycoplasma infection and drug resistance among patients with urogenital tract infection, and provide guidance for clinical reasonable use of antibiotics. Methods The mycoplasma culture and drug sensitivity test were performed by using the mycoplasma detection kits. Results Among 4103 patients, 1336 were infected and the positive rate was 32.56% , including single ureaplasma ttrealyicum （Uu） infections 91.84% （ 1227/1336）, single mycoplasma hominis （Mh） 1.12% （ 15/1336）, and Uu ＋ Mh 7.04% （94/1336）. The results of drug sensitivity showed that the Uu was sensitive to azithromycin, erythromycin, josamycin, roxithromycin, minocycline and doxycycline, while Mh were sensitive to josamyein, minocycline and doxycycline. Conclusion Mycoplasma infection of urogenital tracts was mainly caused by Uu. Because of multi-drug resistance, antibiotics should be chosen according to drug sensitivity test result.