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置管溶栓与单纯抗凝对比治疗下肢深静脉血栓疗效和安全性的Meta分析 被引量:21

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摘要 急性下肢深静脉血栓(deep vein thrombosis,DVT)是一种常见的疾病,发病率及死亡率逐年增高,通过单纯抗凝治疗(anticoagulation,AC)DVT以及应用医用弹力袜预防血栓后综合征(post—thrombotic syndrome,PTS),仍有20%~50%患者在2年内会发展成下肢PTS,急性DVT行Ac治疗,静脉腔内残留大量血栓,导致瓣膜破坏及静脉返流、静脉高压,最终导致PTS。第九版美国胸科医师学会(ACCP)指南认为对于近端急性下肢深静脉血栓的患者,置管溶栓(catheter—directed thrombolysis,CDT)在预防PTS上具有更高的价值。CDT能在最短时间内改善静脉的通畅度,还保留了瓣膜的功能性,可有效预防PTS的发生。本次系统评价汇总分析符合纳入标准的所有研究,目的是评价CDT治疗DVT的疗效和安全性。
出处 《中华普通外科杂志》 CSCD 北大核心 2014年第4期303-306,共4页 Chinese Journal of General Surgery
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共引文献167

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