帕金森病生活质量量表应用及评价

Application and assessment of quality of life questionnaires in Parkinson's disease

帕金森病是中老年人常见的神经变性疾病,临床表现包括运动症状和非运动症状,缓慢进展,严重影响患者生活质量。目前对帕金森病患者生活质量的评价主要依靠量表。本文拟就帕金森病生活质量问卷之通用量表和专用量表,以及显著影响生活质量的帕金森病非运动症状如抑郁和焦虑、认知功能障碍、睡眠障碍和疲劳相关量表进行概述,并对其进行简要评价。

Parkinson＇s disease （PD）, a common neurodegenerative disease in the elderly, is a complex disorder with motor impairment and non-motor manifestations that result in progressive disability and severe complications that have a significant impact on patients＂ quality of life （QoL）. Most of the available QoL instruments depend on written questionnaires. [n this review, current possibilities of evaluation of QoL in Parkinson＇s disease have been critically presented, including universal questionnaires of QoL and the specific ones. The various non-motor symptoms significantly affect patients＂ QoL. Because of that, instruments for the assessment of depression, anxiety, cognitive dysfunction, sleep disorders and fatigue in Parkinson＇s disease were also described.