葛根素注射液治疗急性心肌梗死后心绞痛的临床观察

Clinical observation of Puerarin injection in treatment of angina after acut myocardial infarction

目的 研究葛根素注射液治疗急性心梗后心绞痛的临床效果.方法 收集解放军第二炮兵总医院2010年6月～2013年6月治疗的200例心肌梗死后心绞痛患者,根据治疗方案不同分为治疗组和对照组,对照组患者均予以常规西药治疗;治疗组在常规西药治疗基础上给予葛根素注射液治疗,治疗结束后对比两组在改善心绞痛、心电图、血脂方面的效果.结果 治疗组患者心梗后心绞痛总有效率（92.0％）明显高于对照组（77.0％）,差异有统计学意义（P＜0.05）;治疗组患者心电图总有效率（96.0％）明显高于对照组（78.0％）,差异有统计学意义（P＜0.05）;治疗后治疗组和对照组血脂均有改善,但治疗组患者血脂改善具有统计学意义（P＜0.05）.结论 葛根素注射液治疗心肌梗死后心绞痛临床效果显著,值得推广应用.

Objective To observe the effect of puerarin injection in treatment of angina after acut myocardial infarction. Methods We collected two hundred patients with angina after myocardial infarction from June 2010 to June 2013 in PLA Second Artillery General Hospital. Depending on the treatment plan, they were divided into treatment group and control group,the control group was given conventional western medicine, the treatment group was given puerarin injec- tion on the basis of western medicine, the angina effect, electrocardiogram curative and blood lipid were compared af- ter treatment. Results After treatment, the total effective rate of angina pectoris of treatment group （92.0%）was signifi- cantly higher than that of control group（77.0%）, the difference was statistically significant（P〈0.05） ; the total effective rate of electrbcardiogram of treatment group patients （96.0%）was significantly higher than that of control group （78.0%） ,the difference was statistically significant（P 〈0.05）; the blood lipid of treatment group decreased more significantly than that of control group （P〈0.05）. Conclusion Puerarin injection has remarkable effect on the treatment of angina after myocardial infarction, and it is worth for clinical use.