布地奈德联合沙丁胺醇溶液雾化吸入治疗毛细支气管炎疗效观察

The effect of budesonide and salbutamol inhalation solution in treatment of bronchiolitis

目的观察布地奈德联合沙丁胺醇溶液雾化吸入治疗毛细支气管炎的疗效。方法选择2011年1月～2013年1月入住我院治疗的毛细支气管炎患儿76例，按就诊顺序分为观察组和对照组各38例，对照组予常规治疗。观察组予以布地奈德联合沙丁胺醇溶液雾化吸入治疗，并连用5～7d。结果观察组38例患儿的咳嗽、喘憋、肺部哮鸣音的消失时间明显短于对照组，组间比较，差异有显著性。且观察组患儿的住院时间（7．12±1．36）d，明显短于对照组患儿的住院时间（10．38±1．25）d，组间比较，差异有显著性。两组疗效经秩和检验，观察组的疗效明显优于对照组，组间比较，差异具有显著性（u=2．083，P=0．009）。结论在抗感染、止咳、化痰、镇静吸氧、保持呼吸道通畅等常规治疗的基础上联合布地奈德联合沙丁胺醇溶液雾化吸入治疗毛细支气管炎具有较好的疗效，可以明显改善患儿的临床症状、体征，安全性好，值得推广和应用。

Objective To observe the effect of budesonide and salbutamol inhalation solution in treatment of bronchi- olitis. Methods Seventy-Six patients were divided into two groups 38 cases, control group was given conventional ther- apy. Observation group received budesonide and salbutamol. 5-7 days for a course. Results The 38 cases of children with cough observation group ,wheezing, wheezing lungs disappeared significantly shorter than the control group ,the difference was significant.Observation group＇s hospitalization of children （7.12＋l.36）days,was significantly shorter the control group（10.38＋l.25 days）,the difference was significant.The efficacy of observation group was significantly better than the control group,the difference was significant （u=2.083 ,P=0.009）. Conclusion Anti-infection, cough, phlegm, calming oxygen and maintain airway pateney and other conventional treatment,based on the combined budesonide salbutamol inhalation solution treatment of bronchiolitis and achieved good effect,can significantly improve children clinical symptoms, signs, security is good, and it is worthy of promotion and application.