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健脾养正消癥方对胃癌细胞MGC-803凋亡相关基因表达的影响 被引量:4

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摘要 目的观察健脾养正消癥方体外对胃癌凋亡相关基因表达的影响。方法使用Real-time PCR方法检测该方体外作用于胃癌细胞对凋亡和转移相关基因表达的影响。结果该方体外可导致凋亡相关基因Bax表达上调,Bcl-2、Bclxl、Survivin表达下调。结论健脾养正消癥方可能是通过调节Bax、Bcl-2、Bcl-xl和survivin的表达来发挥诱导凋亡的作用。
出处 《时珍国医国药》 CAS CSCD 北大核心 2014年第4期822-823,共2页 Lishizhen Medicine and Materia Medica Research
基金 国家中医药管理局资助项目(No.JDZX2012086) 江苏省六大人才高峰项目(No.WS037) 国家中医药管理局中医行业科研专项(No.201007007) 江苏省高校优势学科资助项目
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参考文献6

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