穴位注射疗法治疗呃逆的系统评价分析

Acupoin injection therapy on the treatment of Hiccup and the system evaluation analysis

目的通过对收集的穴位注射疗法治疗呃逆有关的文献资料进行筛选、总结及提炼,按照循证医学的原则和方法进行系统评价分析,得出结论,以更好的为医务工作者的临床决策提供证据。方法使用计算机全面检索相关文献,按照拟定的标准筛选、总结及提炼文献信息,并按照Jadad评分量表对纳入研究质量评估,并采用Review manager5.1软件统计测量指标。结果 Meta分析纳入17个研究,异质性检验χ2=25.28,P=0.06,具有临床及统计学意义上的同质性,可用固定模型技能型分析。穴位注射组与对照组比较,合并OR=0.17,95%可信区间为(0.11,0.25),整体效果检验z=8.78,P<0.00001,差异极具有显著性,穴位注射疗法对呃逆的治疗效果优于对照组,但纳入的论文均为低质量论文,存在发表性偏倚,影响结果的真实可靠性。结论纳入Meta分析的论文的质量研究指数偏低且存在潜在发表性偏倚,但是低级证据并不代表无临床实用性,只是其内在真实性可能较低。现有证据表明穴位注射疗法对于呃逆确实有效,施加的干预措施有利于疾病的改善。

Objective Through the collection of water - acupuncture therapy hiccup relevant literature material selection, summa- rize and refining, according to information card medical principle and methods for evaluation and analysis system, draw the con- clusion, in order to better medical workers for clinical decision to provide evidence. Methods Use the computer comprehensive re- trieval relevant literature, according to the standard screening, summarize and refining, according to the literature information jadad rating scale to study the quality evaluation, and into the Review manager 5.1 statistical measurement software. Results Meta analysis into 17 research, and heterogeneous inspection X2 = 25.28, P = 0.06, with clinical and statistical significance of the homogeneity, fixed model skilled analysis can be used. Point injection compared with the control group, the combination OR = 0. 17, 95% confidence interal （0.11, 0. 25 ） , and the overall effect inspection z = 8.78, P 〈 0. 00001, extremely significant differ- ence, water - acupuncture for the therapeutic effect of treatment with hiccup than eontrol group, but in the paper are low quality paper, published bias exist, influence the results to the truth. Conclusion Into the meta analysis of the quality of the thesis re- search index on the low side and potentially published sex bias, but lower low - level evidence doesnt mean no clinical practical, hut their inner reality may be lower. The existing evidence that water - acupuncture therapy for hiccup really effective, applied in- tervention measures conducive to the improvement of the disease.