干细胞立体定向脑内移植治疗高血压脑出血后遗症的临床效果

Effects of the Sequelae of Hypertensive Intracerebral Hemorrhage Treated by Steretaxic Transplantation of Stem Cells

目的:探讨干细胞立体定向脑内移植治疗高血压脑出血后遗症的效果。方法:高血压脑出血后遗症患者40例根据随机数字表法分为治疗组与对照组各20例,对照组给予传统治疗,治疗组应用干细胞立体定向脑内移植治疗。结果:治疗后1个月,治疗组与对照组的有效率分别为35.0%和5.0%,2组对比差异有统计学意义(P<0.05)。随访6个月,治疗组的神经功能缺损评分明显低于对照组,而基本日常生活活动能力评分明显高于对照组(P<0.05)。结论:干细胞立体定向脑内移植治疗高血压脑出血后遗症有较好的近远期效果。

Objective：To discuss the effects of the sequelae of hypertensive intracerebral hemorrhage treated by steretaxic transplanta -tion of stem cells .Methods：40 cases of the sequelae of hypertensive intracerebral hemorrhage were divided into treatment group with 20 cases and control group with 20cases randomly .Control group were treated by traditional therapy .Treatment group were treated by steret-axic transplantation of stem cells .Results：After 1 month of therapy, the efficient rates of treatment group and control group were 35.0%and 5.0 %respectively.The difference was statistically significant （P〈0.05）.The NIHSS of treatment group was significantly lower than control group after 6 months follow-up, and the Barthel Index of treatment group was significantly better than control group （P〈0.05）. Conclusion：The treatment of steretaxic transplantation of stem cells for the sequelae of hypertensive intracerebral hemorrhage could get better effects.