上海市119家医院2010-2012年抗真菌药应用分析

Analysis of the Utilization of Antifungal Agents in 119 Hospitals of Shanghai during 2010-2012

目的:了解上海市抗真菌药的应用情况及变化趋势,为临床应用抗真菌药提供参考。方法:从销售金额、用药频度(DDDs)、日均费用(DDC)等方面分析上海市119家医院2010-2012年抗真菌药的应用情况。结果:3年间抗真菌药的DDDs略有降低,但用药金额和DDC的年复合增长率分别为15.70%、16.16%。这种增长不一致的现象主要来自卡泊芬净和伏立康唑,口服品种中唯一金额增长的是伏立康唑,而注射剂的金额增长主要来自卡泊芬净和伏立康唑。结论:应加强抗真菌药的利用评价工作,进一步促进其合理使用。

OBJECTIVE： To investigate the utilization and tendency of antifungal agents in Shanghai, and to provide reference for rational use of antifungal agents in the clinic. METHODS： The utilization of antifimgal agents in 119 hospitals of Shanghai during 2010-2012 were investigated in respect of consumption sum, DDDs and DDC, etc. RESULTS： The compound annual growth rate of consumption sum and DDC of antifungal agents in 119 hospitals of Shanghai were 15.70% and 16.16%, in spite of the DDDs of antifungal agents decreased slightly. This phenomenon was caused by caspofungin and voriconazole; voriconazole was the only one of oral agents which increased in consumption sum, and caspofungin and voriconazole were injections which increased in consump- tion sum. CONCLUSIONS： The utilization and evaluation of antifungal agents should be emphasized to promote the rational use of thems.