223例药品不良反应报告分析

Adverse Drug Reaction Reported:Analysis of 223 Cases

目的:了解我院药品不良反应(ADR)发生的特点及规律,促进临床合理用药。方法:对我院2005-2012年收集的223例ADR报告进行分析。结果:抗感染药和中药制剂引起的ADR较多,分别占42.60%和29.15%;皮肤及其附件损害的ADR占总报告例次的37.22%;静脉滴注是引起ADR的主要给药途径,占86.55%。结论:临床应加强ADR的监测和报告工作,重视合理用药,以减少和避免ADR的发生,保障患者合理用药。

OBJECTIVE： To investigate the characteristics of ADR in our hospital, and to promote rational drug use in the clin- ic. METHODS： A total of 223 ADR cases reported in our hospital from 2005 to 2012 were analyzed. RESUITS： Most of ADR were caused by antibiotics and TCM preparation, accounting for 42.60% and 29.15%. The lesion of skin and its appendants occu- pied 37.22% of the total cases reported. Intravenous injection was main route of administration in ADR cases （86.55%）. CON- CLUSIONS： Great importance should be attached to ADR monitoring and reporting and rational drug use, so as to reduce and avoid the occurrence of ADR and ensure rational drug use.