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罗格列酮对原发性高血压伴胰岛素抵抗患者的降血压作用 被引量:1

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摘要 目的分析罗格列酮对于原发性高血压合并胰岛素抵抗者的降压效果。方法收集超重或者肥胖且无糖尿病的原发性高血压合并胰岛素抵抗患者120例,随机分为观察组和对照组,各60例,两组患者均予以服用雷米普利治疗,观察组患者在此基础上加服罗格列酮片。结果结束治疗后,观察组患者的SBP、DBP均较治疗前显著降低且处于正常范围,HPMA-IR、FINS及PINS也显著降低,ISI显著升高,P<0.05;观察组的治疗总有效率达96.7%,显著高于对照组的81.7%,P<0.05;两组均未出现肝功能异常及低血糖等严重并发症。结论原发性高血压合并胰岛素抵抗者应用罗格列酮可有效降压,不良反应少,是一种安全可靠、疗效显著的治疗药物。
作者 李蒙
出处 《中国医药指南》 2014年第11期153-154,共2页 Guide of China Medicine
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