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血管内皮生长因子受体的研究进展 被引量：4

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摘要 血管内皮生长因子受体主要在内皮细胞上表达 ,可介导多种生理效应 ,其体内表达水平受低氧及细胞因子等环境因素调节 ,随着现代分子生物学技术的发展 ,对其结构、功能及两者的关系有了较深入的研究 。
作者 姜自彬 李元
机构地区 中国医学科学院/中国协和医科大学医药生物技术研究所
出处 《国外医学（药学分册）》 2001年第1期9-13,共5页 Foreign Medical Sciences(Section of Pharmarcy)
关键词 血管内皮生长因子受体 表达调控 结构 功能 可溶性受体
分类号 R965 [医药卫生—药理学]
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参考文献23

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同被引文献44

  • 1逄小红,田铧,李跃,张凤鸣,金旭.VEGF-C和受体VEGFR-3mRNA在食管鳞癌中的表达及意义[J].中国肿瘤临床,2005,32(20):1152-1154. 被引量：3
  • 2Gille H, Kowalski J, Yu L, et al. A repressor sequene in the juxtamembrance domain of Flt-1(VEGFR-1) constitutively inhibits vascular endothelial growth factor-dependent phosphatidylinositol 3′-kinase activation and endothelial cell migration[J]. EMBO J, 2000, 19(15): 4064-4073.
  • 3Nakopoulou L, Stefanaki K, Panayotopoulou E, et al. Expression of the vascular endothelial growth factor receptor-2/Flk-1 in breast carcinomas: correlation with proliferation[J]. Human Pathology, 2002, 33(9): 863-870.
  • 4Wu L W, Mayo L D, Dunbar J D, et al. Utilization of distinct signaling pathways by receptors for vascular endothelial cell growth factor and other mitogens in the induction of endothelial cell proliferation[J]. J Biol Chem, 2000, 275(7): 5096-5103.
  • 5Veikkola T, Karkkainen M, Claesson-Welsh L, et al. Regulation of angiogenesis via vascular endothelial growth factor receptors[J]. Cancer Res, 2000, 60(2): 203-212.
  • 6Kanno S, Oda N, Abe M, et al. Roles of two VEGF receptors, Flt-1 and KDR, in the signal transduction of VEGF effects in human vascular endothelial cells[J]. Oncogene, 2000, 19(17): 2138-2146.
  • 7Sato Y, Kanno S, Oda N, et al. Properties of two VEGF receptors, Flt-1 and KDR, in signal transduction[J]. Ann N Y Acad Sci, 2000, 902: 201-207.
  • 8Bussolati B, Dunk C, Grohman M, et al. Vascular endothelial growth factor receptor-1 modulates vascular endothelial growth factor-mediated angiogenesis via nitric oxide[J]. Am J Pathol, 2001, 159(3): 993-1008.
  • 9Power C, Wang J H, Sookhai S, et al. Bacterial wall products induce downregulation of vascular endothelial growth factor receptors on endothelial cells via a CD14-dependent mechanism: implications for surgical wound healing[J]. J Surg Res, 2001, 101(2): 138-145.
  • 10Kampfer H, Pfeilschifter J, Frank S. Expressional regulation of angiopoietin-1 and -2 and the tie-1 and -2 receptor tyrosine kinases during cutaneous wound healing: a comparative study of normal and impaired repair[J]. Lab Invest, 2001, 81(3): 361-373.?A

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国外医学（药学分册）
2001年 第1期

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