胃癌淋巴结转移枚数与手术后放射治疗效果的相关性

Correlation of lymph node metastasis and postoperative radiotherapy in gastric carcinoma patients

目的探讨分析胃癌淋巴结转移枚数与术后放疗疗效及相应病理检查结果的相关性。方法 2006年5月至2008年5月收治的胃癌患者,均行胃癌根治性手术治疗,术后诊断为胃癌伴淋巴结转移的患者214例。所有组内淋巴结转移行D2或D3式清扫,且治疗前后均予以放射治疗。结果胃癌患者淋巴结转移枚数与性别、年龄等一般因素无关系,而与肿瘤大小、浸润深度及分期呈正相关。淋巴结转移1~5个、6~9个及〉9个的胃癌患者,其术后及放疗后5年生存率分别为50%、30%和〈10%,三者之间差异有统计学意义（P〈0.05）。结论胃癌患者胃周阳性淋巴结转移数与预后有关,结合肿瘤大小及生长浸润方式可以简便而准确地判断胃癌术后患者的预后情况。

Objective To analyze the correlation between gastric cancer lymph node metastasis number and postoperative radiotherapy curative effect and corresponding pathological findings. Methods Data of 214 patients admiited to our hospital from May 2006 to May 2008 with gastric cancer dignosed by clinical examination receiving radical surgery and with postoperative lymph node metastasis were retrospec- tively analyzed. All cases with lymph node metastasis were cleaned by D2 or D3, and were treated with the radiotherapy both before and after treatment. The relationship among the number of lymph node metastasis, postoperative radiotherapy curative effect and corresponding pathology were summarized. Results Number of positive lymph node metastasis show no relationship in patients with general factors such as gender, age. However,it was positively correlated with tumor size,infiltration depth and staging, Positive metastasis lymph node number l -5,6 ~ 9 and 〉 9 postoperative patients with gastric cancer and 5-year survival rate was 50% ,30% and 〈 10% respectively after radiotherapy ,the differences were statistical significant among the three （P 〈 0. 05 ）. Conclusion Positive lymph node metastasis number is a good prognosis indicator for patients with gastric cance. It is convenient and accurate to judge the prognosis of patients with postopera- tive gastric cancer combined with the tumor size, growth and infiltration.