乌鲁木齐地区汉族男性少、弱精子症危险因素的研究

The research of less sperm and weak sperm risks from han nationality in Urumqi

目的探讨乌鲁木齐市汉族男性少、弱精子症的危险因素,为汉族男性不育症的病因研究、预防干预及生殖健康服务工作提供依据。方法对汉族男性少、弱精子症患者及汉族男性正常健康体检者,进行问卷调查及实验室检查。并将研究对象分为3组,分别为:汉族男性少、弱精子症组,汉族男性健康体检组。分别对汉族男性少、弱精子症组各166人与汉族正常组各166人,进行单因素及多因素Logistic回归分析,找出影响的因素,并分析产生的原因。结果 1.对汉族少精子症而言,有关联的危险因素有禁欲时间(OR=1.194,95%CI:1.067-1.380),对汉族弱精子症而言,有关联的危险因素有棉籽油的食用史(OR=2.115,95%CI:1.250-3.579)。2.汉族少精子症患者使其配偶有流产史不育的危险性高于汉族正常组(OR=0.315,95%CI:0.180-0.550);3.a级精子总数、b级精子总数、pH值、精子活率、d级精子总数、禁欲时间、年龄7个指标对汉族少精子症的贡献比较大;a级精子总数、精子活率、pH值、c级精子总数、精液量5个指标对汉族弱精子症的贡献比较大。结论汉族少精子症与禁欲时间有一定关联;汉族弱精子症与棉籽油的食用史有一定关联。

Objective： This paper is about to study for the risk of the less sperm from Han nationality in Urumqi. Based on the result can be used to support the research of the nosogeny of the sperm less weak risk from the Han nationality which can help to provide the evidence for the reproductive health services. Methods： For han nationality sperm less and weak spermatozoon disease,and han nationality normal physical examination,questionnaire investigation and laboratory examination. Research object is divided into six groups,respectively is： the han nationality sperm less and the weak spermatozoon group,less,the han nationality male physical examination group each 166 people. Analyzed by univariate logistic regression analysis,initial screening risk factors influential,multivariate Logistic regression analysis,further selection of factors have a great impact for han nationality sperm less and weak spermatozoon disease,Make the regression equation,and analyze the causes of the risk factors. Results： 1. For the Han male,the risk of sperm less is related to abstinence time（ OR = 1. 194,95% CI： 1. 067- 1. 380）; The risk for the Han weak spermatozoon disease is related to the cottonseed oil edible history（ OR = 2. 115,95% CI： 1. 250- 3. 579）; 2. Han the spouse has a history of miscarriage risk of infertility is higher than the control group（ OR = 0. 365,95% CI： 0. 215- 0. 618）; 3. For age,abstinence time,semen pH value（ pH）,the total number of sperm,sperm b,d level of total number of sperm and live sperm rate total seven indicators have a larger contribution to the han nationality sperm less; Sperm quantity,pH value（ pH）,forward movement level sperm counts,sperm and live sperm rate total contributions to the han weak spermatozoon disease is larger. Conclusion： The risk of Han sperm less is related to abstinence time; the risk for the Han weak spermatozoon disease is related to the cottonseed oil edible history; han less sperm can lead to their spouse.