艾叶油对豚鼠平喘作用的实验研究

Study on the Effect of volatile oil from Artemisia argyi on Bronchial Asthma

目的:研究艾叶油的平喘作用。方法:豚鼠随机分成模型对照组、阳性药物组(离体实验为心得安,整体实验为异丙肾上腺素)和艾叶油高、中、低剂量组,以豚鼠离体气管片实验和豚鼠哮喘模型,研究艾叶油的平喘作用。结果:艾叶油可直接舒张豚鼠离体气管平滑肌;对豚鼠哮喘模型,艾叶油能延长哮喘发作的潜伏时间。结论:艾叶油具有平喘作用。

Objective To study on the effect of volatile oil from Artemisia argyi （VOFAA） on bronchial asthma. Methods The Guinea pigs were randomly divided into five groups： control, propranolol in vitro or isoprenaline in vivo, and VOFAA of high dose, VOFAA of moderate dose, VOFAA of low dose. Adopted the Guinea pig＇s tracheal slice test in vitro and asthma test in vivo respectively to study the effect of VOFAA on bronchial asthma. Results VOFAA with all three doses showed the effect of the relaxation of the contractive tracheal slices in vitro, and the prolongation of the asthma delitescence in vivo. Conclusion VOFAA has positive effect on bronchial asthma.