卡维地洛治疗扩张型心肌病89例疗效观察

The efficacy of 89 dilated cardiomyopathy cases treated by the carvedilol

目的 观察卡维地洛治疗扩张型心肌病的临床疗效.方法 回顾性分析89例扩张型心肌病应用卡维地洛患者的临床资料.结果 总有效率98.88％,停药后死亡1例;治疗前、后左室腔收缩期内径（LVDD）分别为（68.25 ±2.15）mm、（56.89±4.21）mm,左室射血分数（LVEF）分别为（28.63±0.33）％、（40.56±3.98）％,差异均有统计学意义（t =7.215、16.877,均P＜0.05）.结论 卡维地洛治疗扩张型心肌病临床效果较好.

Objective To analyse the therapeutic effect of Carvedilol in patients with severe heart failure.Methods The clinical data of 89 Carvedilol patients treated with dilated cardiomyopathy were retrospective analysis.Results The overall therapeutic effective rate was 98.88%,because of one death related to discontinued use of medication.Before and after treatment,systolic left ventricular cavity diameter （LVDD） were （68.25 ＆#177; 2.15） mm,（56.89 ＆#177;4.21） mm,respectively,and left ventricular ejection fraction（LVEF） were （28.63 ＆#177;0.33）%,（40.56 ＆#177;3.98） %,respectively,there were significantly differences （t =7.215,16.877,all P 〈 0.05）.Conclusion Carvedilol is the cornerstone in the drug treatments of patients with dilated cardiomyopathy.