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对氧磷酶-1与多囊卵巢综合征的相关性研究 被引量:1

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摘要 目的 探讨对氧磷酶-1(PON-1)与多囊卵巢综合征(PCOS)的相关性.方法 测定并比较肥胖和非肥胖PCOS妇女与健康妇女血清PON-1水平变化及差异.结果 PCOS肥胖妇女及PCOS非肥胖妇女血清PON-1水平[(59±4)mmol/L、(76±4) mmol/L]显著低于健康对照组(109±7) mmol/L(F =54.51,P<0.01),其中以PCOS肥胖妇女最低.结论 测量血清PON-1水平对评估PCOS妇女罹患心血管疾病的风险有较大的意义.PON-1活性降低提示体内存在氧化应激状态,是导致部分PCOS发生的重要因素.
出处 《中国基层医药》 CAS 2014年第8期1195-1197,共3页 Chinese Journal of Primary Medicine and Pharmacy
基金 广东省深圳市福田区卫生公益性科研项目
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