双靶点微创血肿抽吸引流术治疗基底节区大面积脑出血的临床对照研究

Clinical study on double-target minimally invasive hematoma aspiration in treatment of massive ganglionic hemorrhage

目的:研究双靶点微创血肿抽吸引流术治疗基底节区大面积脑出血的疗效与安全性。方法:接受微创血肿抽吸引流术的基底节区脑出血患者68例,随机选取34例患者接受单靶点穿刺,其余患者行双靶点穿刺。比较2组血肿清除率、血肿清除速度和并发症发生情况。结果:双靶点组的血肿清除率、绝对血肿清除速度和相对血肿清除速度都明显优于单靶点组(均P<0.05)。2组患者的术后再出血、颅外并发症的发生率差异均无统计学意义。2组患者的长期预后也是一致的。结论:对于基底节区大面积脑出血,双靶点抽吸引流比单靶点更能有效清除血肿,且两者间的安全性无差异。

Objective： To investigate the effect and safety of double-target minimally invasive hematoma aspiration in treatment of massive ganglionic hemorrhage. Methods： Sixty-eight cerebral basilar hemorrhage patients treated with micro-in- vasive procedure were randomly divided into double-target group （34 cases）and single-target group （34cases）. The hemato- ma clearance rate, clearance speed and complications were compared between two groups. Results： The hematoma clearance rate, absolute and relative clearance speed in double-target group were significantly superior to those of single-target group （ P 〈0.05）. But no significant difference was noted in terms of the postoperative complications and long-term prognosis. Conclusions： The double-target puncture may be more effective to remove clot than the single-target in minimally iuvasive hematoma aspiration for massive ganglionic hemorrhage. This procedure represented no increased risks of postoperative complication compared with the single-target puncture.