NBI+放大联合碘染色对早期食管癌及癌前病变的诊断价值探讨

Clinical Value of Narrow-band Imaging(NBI) plus Amplification Combined with Iodine Staining on the Diagnosis for Early Esophageal Cancer and Precancerous Lesions

[目的]探讨窄带成像技术(NBI)+放大联合碘染色对早期食管癌及癌前病变的诊断价值。[方法]173例早期食管癌及癌前病变患者,共183个病变,分别在普通模式和NBI模式下观察食管黏膜,用NBI放大观察病变的腺管开口形态及毛细血管结构形态并分型,然后应用1.5%碘液行全食管染色,对所有NBI阳性和碘染色阳性部位取活检,所有病变均以病理结果作为诊断标准。[结果]普通模式下发现病变134个(73.22%),NBI结合碘染色发现病变183个(100.0%)。[结论]NBI可清晰显示早期食管癌、癌前病变的腺管开口及毛细血管结构形态,NBI联合碘染色对早期食管癌和癌前病变的诊断率明显优于普通内镜。

[Purpose] To investigate the diagnosis value of narrow-band imaging （NBI） plus am- plification combined with iodine staining for early esophageal cancer and precancerous lesions. [Methods] A total of 173 cases （183 lesions） with early esophageal cancer and precancerous lesions were observed under normal mode and NBI esophageal mucosa, with NBI magnification lesions opening shape of the gland and capillary structure form and classification. 1.5% iodine liquid dye was applied on whole esophagus. All lesions were diagnosed by pathological results as the standard. [Resultsl One hundred and thirty four lesions （73.22%） were found by com- mon mode,and 183 lesions（lO0.0%） by NBI combined with iodine staining,with significant difference （P〈0.05）. [Conclusion] NBI can clearly display early esophageal cancer and precancerous le- sions in the mouth of the gland and capillary structure form. NBI combined with iodine staining is better than ordinary endoscopy.