摘要
In this study, the possibility of preparation and application of highly porous silica aerogel-based bioactive materials are presented. The aerogel was combined with hydroxyapatite and p.tricalcium phosphate as bioactive and osteoinductive agents. The porosity of aerogels was in themesoporous region with a maximum pore diameter of 7,4 and 12.7 nm for the composite materials. The newly developed bioactive materials were characterized by scant electron microscopy. The in vitro biological effect of these modified surfaces was also tested on SAOS-2 osteogenic sarcoma cells by confocal laser scanning microscopy.
In this study, the possibility of preparation and application of highly porous silica aerogel-based bioactive materials are presented. The aerogel was combined with hydroxyapatite and p.tricalcium phosphate as bioactive and osteoinductive agents. The porosity of aerogels was in themesoporous region with a maximum pore diameter of 7,4 and 12.7 nm for the composite materials. The newly developed bioactive materials were characterized by scant electron microscopy. The in vitro biological effect of these modified surfaces was also tested on SAOS-2 osteogenic sarcoma cells by confocal laser scanning microscopy.
