偏振光散射无标记活体“显微”成像技术研究进展

Progress In Polarized Light Scattering Microscopic In Vivo Imaging Techniques

偏振光测量是一种用来探究物质结构和形态的有效方法。偏振光散射测量可以通过介质的偏振特性得到微观结构和形态信息,并可以提高样品浅层成像分辨率,从而减小光学成像受散射的影响。偏振光散射测量具有光学方法的非侵入、无损伤、快速测量等优势,在生物医学以及材料、海洋、大气等领域都有很好的应用前景,特别是在癌变检测方面的潜力尤其引人注目。本文通过介绍偏振光散射测量的相关方法及研究进展来分析目前偏振光学成像在生物医学等领域的发展状况,以及未来发展的前景。

Polarized light scattering properties are suitable for the detections of the micro-structure variations of turbid media, and can be used to improve the imaging resolution of superficial layers of samples. Polarization scattering techniques are no invasive, non-destructive and rapid measurement methods. Therefore, they are potentially powerful tools for the analysis material, oceanic and atmosphere samples. Recently, polarization scattering imaging techniques are used for the detection n- of of cancerous tissues. In this paper, we introduced the progress in polarized light scattering microscopic in vivo imaging techniques for biomedical diagnosis