甲哌卡因用于肌间沟臂丛阻滞麻醉的临床观察

Clinical Observation on the Intersclance Brachial Plexus Block Anesthesia with Mepivacaine

目的:观察甲哌卡因用于肌间沟臂丛阻滞麻醉中的有效性、安全性和可行性。方法:肌间沟臂从阻滞麻醉下行上肢手术75例随机分为利多卡因组(1.5%利多卡因麻醉)、罗哌卡因组(0.375%罗哌卡因麻醉)和甲哌卡因组(1.5%甲哌卡因麻醉),每组25例。比较3组的麻醉起效时间、作用时效、运动阻滞时间和注药后30 min运动阻滞程度、不良反应。结果:与利多卡因和罗哌卡因组比,甲哌卡因组麻醉起效时间、作用时效、注药后30 min运动阻滞程度差异有统计学意义(P<0.05)。利多卡因组需用地佐辛镇痛3例;罗哌卡因组术侧上眼睑下垂2例、声嘶4例;甲哌卡因组声嘶1例。结论:甲哌卡因用于肌间沟臂丛阻滞麻醉效果好,不良反应少,安全、可靠。

Objective：To observe the effectiveness,safety and feasibility of the interscalene brachial plexus block anesthesia with mepivacaine. Methods：Senventy-five patients with upper limb operation undergone interscalene brachial plexus block anesthesia were randomly divided into lidocaine（1.5% lidocaine）,ropivacaine（0.375% ropivacaine）and mepivacaine（1.5% mepivacaine） groups,25 patients in each group. The anesthesia onset time,effect time,motor block time and 30 minutes after injection,adverse reactions were compared among groups. Results：Compared with lidocaine and ropivacaine groups,the onset time of anesthesia, time effect of 30 minutes after injection,motor block degree in the mepivacaine group had statistical significant（P0.05）. There were 3 cases with dezocine in the lidocaine group,2 cases with ptosis of upper eyelid and 4 cases with hoarseness in the ropivacaine group,one cases with hoarseness in the mepivacaine group. Conclusion：Mepivacaine,with less adverse reactions and safe,can achieve satisfactory effect for interscalene brachial plexus block anesthesia.