儿童恙虫病50例临床分析

Clinical analysis of 50 children with tsutsugmushi disease.

目的探讨儿童恙虫病临床特征并分析本病的治疗效果。方法对2005年1月-2012年12月收治的50例恙虫病的临床资料进行回顾性分析。结果50例患儿均有发热，大部分发现有焦痂或淋巴结肿大；32例血常规白细胞正常或偏低，12例血红蛋白少于90g／L，12例血小板少于100×10^9／L。15例并发肺部炎症，贫血12例，呼吸衰竭2例，心力衰竭1例，中毒性肝炎12例，肾损害8例，多器官功能损害3例。治愈率为100％，无死亡及无复发病例。结论恙虫病可累及肝、肺、心脏、血液、神经等器官、系统，结合流行病学史及焦痂或特异性溃疡是确诊恙虫病的最重要依据。

Objective To analyze the clinical characteristics of children with tsutsugamushi disease. Methods Fifty child patients with tsutsugamushi disease in our hospital from January 2010 to December 2012 were retrospectively analyzed. Results Fever occurred to all the eases, eschar or swollen lymph nodes were observed in a majority of the cases. White blood ceils were either normal or lower in 32 cases, the level of hemoglobin in 12v cases was less than 90g/L, platelet in another 12 cases was less than 100 × 10^9 / L.. Fifteen cases were complicated with pulmonary inflammation, anemia occurred to 12 cases, respiratory failure was noticed in 2 cases, heart failure was observed in 1 case, 12 cases were with intoxicated hepatitis, renal damage occurred to 8 cases and 3 eases with multiple organ dysfunction. The cure rate was 100% without recurrence. Conclusion Tsutsugamushi disease implicates the liver, lung, heart, blood, nerve and other organs and systems. Diagnosis of the disease is based on the eschar or specific ulcer in combination with epidemiological history of the cases..