12例子宫腺肌瘤保守手术疗效分析

Curative effect analysis of 12 cases of adenomyoma conservative surgery

目的：探讨子宫腺肌瘤保守手术的可行性。方法回顾性分析本院行保守手术的12例子宫腺肌瘤患者的临床资料。结果12例均采用开腹手术,行保守性手术（局部病灶挖除术）,手术顺利,术后予以药物配合左炔诺孕酮缓释系统（LNG-IUS）治疗,随访2-48个月,痛经全部缓解, CA125术前56.4-231.2 U/ml,平均值为（94.55±51.25）U/ml,术后6个月下降明显,平均值为（32.17±11.61）U/ml,和术前相比差异有统计学意义（t=4.656, P=0.001）。随诊超过6个月者10例（83.3%）,复发率0%；不孕者2例,其中1例已孕32周。结论对于要求保留子宫的子宫腺肌瘤患者,在充分知情沟通下,行局部病灶挖除术,术后配合药物治疗是可行的,且近期复发率低。

Objective To study the feasibility of uterine adenomyoma conservative Surgery. Methods Retros-pectively analyzed the clinical data of 12 cases of uterine adenomyoma of our hospital conservative surgery. Results 12 cases with open operation, with （local lesion invisible） conservative surgery, surgery goes well, postoperative left acetylene connaught progesterone slow-release system be drugs （LNG IUS） treatment, followed up for 2 to 48 months, all alleviate dysmenorrhea, CA125 preoperative 56.4-231.2 U/ml, average （94.55±51.25） U/ml, decreased significantly after 6 months, the average （32.17±11.61）U/ml, compared with the preoperative difference was statistically significant （t=4.656, P=4.656）. Follow-up more than 6 months 10 cases （83.3%）, recurrence rate 0%;infertility in 2 cases, one was at 32 weeks. Conclusion For reserve uterus myoma of uterus gland, under fully familiar with the communication, the invisible line local lesions, postoperative cooperate with drug treatment is feasible, and recent recurrencerate is low.