肝脏少部分切除术中血小板凝胶的应用

Application of platelet gel in less partial hepatic resection

目的:研究血小板凝胶在肝脏部分切除术中应用的临床效果及其对术后患者的影响。方法:选取62例原发性肝癌及其他肝良性占位性病变行肝脏部分切除患者,随机分为2组:实验组31例,在肝脏部分切除后,缺损处用血小板凝胶封闭,并以明胶海绵剪成多块小片段混合血小板凝胶以覆盖断面来代替常规缝合;对照组31例仅缝合收拢肝组织缺损。结果:实验组使用的血小板凝胶可迅速附着于创面,患者肝脏部分切除的手术时间、出血量均小于对照组,引流量及渗血持续时间均明显小于对照组(P<0.05),实验组出院时间比对照组平均提前2d。结论:在肝脏部分切除中应用血小板凝胶可以有效降低手术时间、减少肝部分切除后出血,促进创面愈合,缩短住院时间,值得临床推广应用。

Objective： To study the clinical effect of platelet gel in partial hepatic resection and its effect on postoperative patients. Method： 62 patients with primary liver cancer and other benign liver lesions underwent liver resection fFrom 2009 January to 2012 December were randomly divided into two groups. 31 cases in experimental group, after partial hepatectomy, the defect were enclosed with platelet gel, and gelatin sponge was cut into pieces and mixed with platelets gel to cover section instead of the conventional, suture. 31 cases of the control group was only closed hepatic tissue defect by suture. Result： The platelet gel used in the experimental group could quickly attach to the wound, and the liver resection operation time and bleeding amount were lower than those of control group, drainage amount and hemosshage duration were significantly less than that of control group （P〈0.05）. The discharge time of experimental group was an average of 2 days in advance than control group. Conclusion.. Application of platelet gel in liver resection could effectively reduce operation time, reduce bleeding after partial hepatectomy, promote wound healing and shorten the time of hospitalization, which would be worthy of clinical application.