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SLC30A8基因rs13266634多态性与中国东乡族2型糖尿病的关系 被引量:1

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摘要 明确溶质载体家族30成员8(SLC30A8)基因rs13266634单核苷酸多态性(SNP)在中国东乡族的分布及其与2型糖尿病的关系.应用聚合酶链反应-限制性片段长度多态性(PCR-RFLP)方法对中国东乡族人群rs13266634的基因型进行分析.2型糖尿病组(T2DM组)rs13266634的CC基因型频率、C等位基因的频率均显著高于正常对照组(NC组)(P<0.05),C等位基因携带者患2型糖尿病的风险是T等位基因的1.62倍(OR=1.62,95%CI为1.13~2.31).中国东乡族人群存在SLC30A8基因rs13266634位点变异,其C等位基因是2型糖尿病的风险等位基因,SLC30A8基因是中国东乡族人群2型糖尿病的易感基因之一.
出处 《甘肃科技》 2014年第7期138-139,共2页 Gansu Science and Technology
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