肥厚型心肌病患者左心室舒张同步性的二维斑点追踪成像研究

Evaluation of left ventricular diastolic synchronism in patients with hypertrophic cardiomyopathy by two dimensional speckle tracking imaging

目的 :应用二维斑点追踪成像技术(2D-STI)分析肥厚型心肌病(HCM)患者的左心室舒张同步性。方法:选取47例HCM患者(HCM组)与33例健康体检者(对照组)。应用2D-STI分别测量左心室各节段舒张早期、晚期的纵向、径向以及圆周应变率达峰时间(TESRL、TASRL、TESRR、TASRR、TESRC、TASRC),并计算左心室整体舒张早期、晚期的纵向、径向及圆周应变率达峰时间标准差(TESRL-SD、TASRL-SD、TESRRSD、TASRR-SD、TESRC-SD、TASRC-SD),比较两组上述参数。结果:HCM组的TESRL-SD、TESRR-SD、TESRC-SD及TASRL-SD明显大于对照组(P<0.001或P<0.01),而TASRR-SD及TASRC-SD较对照组有增大趋势,但差异无统计学意义(P>0.05)。结论:HCM患者左心室舒张存在显著失同步,2D-STI为HCM舒张失同步的评价提供了新的方法。

To evaluate diastole synchrony of the different segments of left ventricular in patients with hypertrophic cardiomyopathy by two dimensional speckle tracking imaging. Methods： Forty-seven patients with HCM and thirty-three healthy volunteers were studied by two dimensional speckle tracking imaging.The peak time of early and late diastolic longitudinal, radial, circumferential strain rate were measured from the start point of QRS wave of electrocardiogram. The left ventricular segmental standard deviation （TEsRL-SD, TASRL-SD, TESRR-SD, TASRR-SD, TESRc-SD, TASRc-SD） were calculated, which were served as diastolic synchronism indexes in assessing LV diastolic aspect. Results： TESRL-SD, TESRR-SD, TESRc-SD and TASRL-SD were significantly higher in patients with HCM than those in normal controls. TASp, R-SD and TASRc-SD were higher in patients with HCM than those in normal controls, but the difference had no statistical significance. Conclusion： Left ventricular diastole dyssynchrony can be evaluated accurately in patients with hypertrophic cardiomvooathv bv two dimensional soeckle trackin~ ima^in~.