94853例恶性肿瘤住院患者疾病构成及死因分析

Analysis of disease constitute and death causes of 94 853 cancer inpatients

目的:分析肿瘤住院患者的疾病构成及主要死亡原因。方法:回顾性分析2002年至2012年四川省肿瘤医院94 853例肿瘤住院患者的临床资料。结果:2002年至2012年恶性肿瘤住院患者前10位的疾病类型分别为肺癌、宫颈癌、食管癌、乳腺癌、结直肠癌、鼻咽癌、肝癌、胃癌、淋巴瘤、卵巢癌,占全部恶性肿瘤住院患者的82.0%。住院患者总病死率为2.7%,男性总病死率为3.4%高于女性2.0%(P<0.001);2002年至2012年肿瘤住院患者男、女及总病死率均呈明显下降趋势(P<0.001)。恶性肿瘤死亡患者的前10位死因依次为肺癌、肝癌、结直肠癌、食管癌、胃癌、淋巴瘤、乳腺癌、胰腺癌、卵巢癌、鼻咽癌,占死亡总数的81.3%;其中,胰腺癌的病死率最高(9.6%),鼻咽癌最低(1.08%)。不同性别死亡患者有不同的死因顺位,前10位死因顺位中,男性食管癌的病死率高于女性(P=0.046),女性胃癌病死率高于男性(P=0.003)。不同年龄段死亡患者有不同的死因顺位,前10位死因顺位中,肺癌、肝癌、结直肠癌、乳腺癌在60岁以上人群的病死率最高(P<0.001)。结论:四川省肿瘤医院肿瘤住院患者的疾病构成及死因分析为肿瘤防治工作提供了依据,肺癌、宫颈癌、食管癌是我省须重点防治的肿瘤。

Objective：To understand the disease constitute and the death causes of cancer inpatients .Methods：Statistical analysis of 94 853 cancer inpatients from 2002 to 2012 in Sichuan Cancer Hospital was retrospectively conducted .Results：From 2002 to 2012 in patients with malignant tumor in the top 10 disease types were lung cancer , cervical cancer , esophageal cancer , breast cancer , colorectal cancer , nasopharyngeal carcinoma , liver cancer, gastric cancer, lymphoma, ovarian cancer, accounting for 82% of all malignant tumor patients.Total hospital mortality of patients was 2.7%, total male mortality was 3.4% higher than that of female 2% （ P 〈0.001） from 2002 to 2012; tumor patients in hospital with male , female and total mortality were significantly decreased （ P〈0.001 ） .The 10 leading causes of death of malignant tumors in patients with lung cancer , liver＆amp;nbsp;cancer , as follows： colorectal cancer , esophageal cancer , gastric cancer , lymphoma , breast cancer , pancreatic cancer , ovarian cancer , nasopharyngeal carcinoma , accounting for 81.3%of the total deaths;wherein , pancreatic cancer has the highest mortality was 9.6%, the lowest of 1.08% nasopharyngeal carcinoma .The patients had different causes of death between male and females;among the top 10 causes of death , there was a higher mortality rate for esophageal cancer in male than in female （ P=0.046 ） , and a higher gastric cancer mortality in women than men （ P=0.003 ） .The patients of different ages had different causes of death , among the top 10 causes of death, lung cancer, liver cancer, colorectal cancer, breast cancer in people over the age of 60 had a higher mortality rate （ P〈0.001 ） .Conclusion： The constitution of in-patient in Sichuan Cancer Hospital is defined , which could provide a scientific basis for disease prevention and control .Lung cancer , cervical cancer , esophageal cancer were important turnors need to focus on prevention and treatment .