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microRNA在卵巢和卵巢癌中的表达及功能 被引量：3

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摘要 微小 RNA （ miRNA ）是一种内源性的非编码小 RNA （18-25个核苷酸），通过降解靶mRNA或抑制其翻译，对基因进行转录后水平的调控。 miRNA参与调控多个生物学过程，有望成为治疗相关疾病的重要靶点。 miRNA在卵巢生理病理过程中发挥着重要的调控作用，其表达的缺失或过表达会显著影响卵巢的生理功能，部分miRNA还作为促癌或抑癌因子参与调控卵巢癌的发生发展过程。现对近年来miRNA在女性卵巢生理过程和卵巢癌中的表达情况及生物功能进行综述。
作者 朱清 许波 刘雨生
机构地区 安徽医科大学附属省立医院生殖中心
出处 《安徽医科大学学报》 CAS 北大核心 2014年第5期694-697,共4页 Acta Universitatis Medicinalis Anhui
基金 安徽省自然科学基金(编号:1308085Qh131)
关键词 微RNAS 卵巢 卵巢肿瘤
分类号 R342.2 [医药卫生—基础医学] R339.221 [医药卫生—人体生理学]
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参考文献30

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同被引文献25

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安徽医科大学学报
2014年 第5期

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