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卵巢早衰诊治进展 被引量:20

Progress of Diagnosis and Treatment of Premature Ovarian Failure
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摘要 卵巢早衰(premature ovarian failure,POF)是妇科内分泌领域常见的疾病,病因复杂多样,遗传、自身免疫性疾病、感染、医源性因素等均可引起POF,但超过50%的POF患者病因不清。POF临床表现复杂多样,早期诊断困难,确诊平均需要5年。阴道超声、激素水平、抗苗勒管激素及抑制素B等在一定程度能预测卵巢功能。POF对患者身心健康产生重要影响,因此其早期诊断与治疗至关重要。目前主要治疗方法是激素替代疗法缓解绝经症状、赠卵辅助生殖技术解决生育问题。自身卵巢移植术、卵巢及卵泡冷冻技术等新方法给患者带来希望。 Premature ovarian failure (POF) is a common gynecologic endocrine disease. The cause of POF is complex and diverse. Genetic,autoimmune disease,infection,iatrogenic factors all can induce POF,but the etiology of more than 50%POF patients is still unclear. The clinical manifestations of POF are complex and varied ,early diagnosis is difficult and it takes an average of five years to be confirmed. Vaginal ultrasound,hormone level determination,anti-Müllerian hormone and inhibin B can predict ovarian function in a certain degree. Because of significant impact on physical and psychological health ,early diagnosis and treatment are significantly important. For POF patients ,hormone replacement is the main therapy to relieve menopausal symptoms,but donating oocyte for IVF is the important method to solve fertility problems. Self-ovarian transplantation,ovarian and follicle vitrification technologies bring more hope for the infertility patients.
出处 《国际妇产科学杂志》 CAS 2014年第2期108-111,共4页 Journal of International Obstetrics and Gynecology
关键词 卵巢功能早衰 激素替代疗法 自身免疫疾病 组织移植 Ovarian failure,premature Hormone replacement therapy Autoimmune diseases Tissue transplantation
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  • 1Kokcu A. Premature ovarian failure from current perspective [J]. Gynecol Endocrinol, 2010,26(8 ) : 555-562.
  • 2Brranger R,Hoffmann P, Christin -Maitre S,et al. Occupational exposures to chemicals as a possible etiology in premature ovarian failure : a critical analysis of the literature[J]. Reprod Toxieol, 2012, 33(3) :269-279.
  • 3Ghassemzadeh A,Farzadi L, Beyhaghi E. Premature ovarian failure risk factors in an Iranian population[J]. Int J Gen Med, 2012,5:335- 338.
  • 4穆玉兰,秦莹莹,夏铭笛,陈子江.评价卵巢衰老指标的研究进展[J].中华临床医师杂志(电子版),2011,5(16):4835-4837. 被引量:7
  • 5Shelling AN. Premature ovarian failure [J]. Reproduction, 2010,140 (5):633-641.
  • 6Maclaran K,Panay N. Premature ovarian failure [J]. J Faro Plann Reprod Health Care, 2011,37( 1 ) : 35-42.
  • 7王伟群,张华,梁伟翔,蔡款,周星星.卵巢早衰患者卵巢大小及血流动力学参数与性激素水平的相关性[J].中华医学超声杂志(电子版),2011,8(10):2160-2164. 被引量:18
  • 8Braham R, Hidar S, Chaieb M, et al. Place of pelvic ultrasonography using transabdominal technique in the investigation of premature ovarian failure[J]. Ann Endocrinol (Paris), 2010,71 (4) : 286-290.
  • 9Jiao X, Qin C, Li J,et al. Cytogenetic analysis of 531 Chinese Women with premature ovarian failure[J]. Hum Reprod, 2012,27 ( 7 ) : 2201 - 2207.
  • 10Cordts EB, Christofolini DM, Dos Santos AA, et al. Genetic aspects of premature ovarian failure: a literature review[J]. Arch Gynecol Obstet, 2011,283(3 ) : 635-643.

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