1Yang SH,Dou KF,Song WJ.Prevalence of diabetes among men and women in China[J].N Engl J Med,2010,362 (25):2425-2426.
2Joh HK,Willett WC,Cho E.Type 2 diabetes and the risk of renal cell cancer in women[J].Diabetes Care,2011,34 (7):1552-1556.
3Zhu Z,Zhang X,Shen Z,et al.Diabetes mellitus and risk of bladder cancer:a meta-analysis of cohort studies[J].PLoS One,2013,8(2):e56662.
4Evans JM,Donnelly LA,Emslie-Smith AM,et al.Mefformin and reduced risk of cancer in diabetic patients[J].BMJ,2005,330 (7503):1304-1305.
5Col NF, Ochs L, Springmann V, et al. Metformin and breast canc- er risk : a meta-analysis and critical literature review [ J ], Breast Cancer Res Treat, 2012,135 (3) :639-646.
6Fujita-Hamabe W,Harada S,Tokuyama S.[Effectiveness of metformin in prevention of development of hyperglycemia and neuronal damage caused by ischemic stress] [J].Yakugaku Zasshi,2011,131 (4):533-538.
7Viollet B,Andreelli F.AMP-activated protein kinase and metabolic control[J].Handb Exp Pharmacol,2011,(203):303-330.
8Ishibashi Y,Matsui T,Takeuchi M,et al.Metformin inhibits advanced glycation end products (AGEs)-induced growth and VEGF expression in MCF-7 breast cancer cells by suppressing AGEs receptor expression via AMP-activated protein kinase[J].Horm Metab Res,2013,45 (5):387-390.
9Hirsch HA,Iliopoulos D,Tsichlis PN,et al.Metformin selectively targets cancer stem cells,and acts together with chemotherapy to block tumor growth and prolong remission[J].Cancer Res,2009,69(19):7507-7511.
10Vasquez-Martin A,Oliveras-Ferraros C,Cuff S,et al.Metformin regulates breast cancer stem cell ontogeny by transcriptional regulation of the epithelial-mesenchymal transition (EMT) status[J].Cell Cycle,2010,9(18):3807-3814.
