糠酸莫米松乳膏联合复方甘草酸苷片治疗慢性湿疹临床近期疗效观察

Clinical short-term efficacy observation of mometasone furoate cream combined with compound glycyrrhizin tablets in treatment of chronic eczema

目的观察糠酸莫米松乳膏联合复方甘草酸苷片治疗慢性湿疹的临床近期疗效。方法将66例慢性湿疹患者,随机分为治疗组36例,对照组30例,疗程均为4周,治疗组用糠酸莫米松乳膏均匀涂于患处,1次/日,并且口服复方甘草酸苷片,3次/日,2片/次,对照组单纯外用糠酸莫米松乳膏均匀涂于患处,1次/日。结果治疗组痊愈22例,痊愈率61.1%,总有效32例,总有效率88.9%;对照组痊愈12例,痊愈率40.0%,总有效17例,总有效率56.7%,治疗组与对照组临床疗效相比差异有统计学意义(x2=13.7,P<0.05)。结论?糠酸莫米松乳膏联合复方甘草酸苷片治疗慢性湿疹比单纯外用糠酸莫米松乳膏临床近期疗效好,是治疗慢性湿疹的较好方法之一。

Objective To observe the clinical short-term efficacy of mometasone furpate cream combined with compound glyeyrrhizin tablets in the treatment of chronic eczema. Methods Sixty-six patients with chronic eczema were randomly divided into the treatment group with 36 patients and the control group with 30 patients; The treatment course was 4 weeks for both groups; The treatment group received mometasone furoate cream evenly applied to the affected area once/day and oral administration of compound glycyrrhizin tablets 3 times/day and 2 tablets/time. The control group received simple external application of mometasone furoate cream evenly applied to the affected area once/day. Results In the treatment group; 22 patients recovered, with a recovery rate of 61.1%, and 32 patients were effective, with a total effective rate of 88.9%; In the control group, 12 patients recovered, with a recovery rate of 40.0%, and 17 patients were effective, with a total effective rate of 56.7%; The treatment group and the control group had statistically different clinical efficacy （Х^2=13.7, P 〈 0.05）. Conclusion Mometasone furoate cream combined with compound glycyrrhizin tablets shows better clinical short-term efficacy than simple external application of mometasone furoate cream and therefore is a good method to treat chronic eczema.