手足口病采用酪酸梭菌活菌散辅助治疗的临床效果分析

Analysis of clinical effects of clostridium butyricum viable bacteria powder in adjuvant treatment of Hand-Foot-Mouth disease

目的探讨酪酸梭菌活菌散治疗手足口病的临床疗效。方法选取我院2012年6月-2013年12月收治的80例手足口病患儿为研究对象，将其按照时间的顺序平均分成A组与B组，各50例。A组患儿给予酪酸梭菌活菌散治疗，B组患儿给予常规手足口病疗法，观察两组临床治疗效果。结果A组患儿临床治疗的起效时间、疱疹消失时间、食欲正常时间、体温恢复正常时间等均较B组短，差异均具有统计学意义（P〈0．05）；A组患儿临床治疗总有效率为98．0％；B组患儿总有效率为76．0％，A组患者临床效果明显优于B组，差异具有统计学意义（P〈0．05）；两组患儿均未发生较严重的不良反应。结论酪酸梭菌活菌散治疗手足口病的临床疗效较为显著，能在较短的时间内改善患者临床症状，值得应用推广。

Objective To observe and evaluate the clinical efficacy of Clostridium butyricum viable bacteria powder in the treatment of hand-foot-mouth disease （HFMD）. Methods Eighty children with HFMD treated in our hospital from June 2012 to December 2013 were selected as the study subjects and evenly divided into group A and group B according to the time sequence,with 50 children in each group.Group A received Clostridium butyricum viable bacteria powder treatment and group B received conventional HFMD treatment.The clinical treatment effects of the two groups were observed. Results Group A was shorter than group B in the clinical treatment onset time,herpes disappearance time, normal appetite restoration time and normal body temperature restoration time, with statistically significant differences for all （P 〈 0.05）.The total effective rate of clinical treatment of group A was 98.0% and that of group B was 76.0%;Group A had significantly better clinical effects than group B,with statistically significant difference （P 〈 O.05）.Neither group had severe adverse reactions. Conclusion In the treatment of HFMD, Clostridium butyricum viable bacteria powder shows remarkable clinical efficacy and can improve the patients＇ clinical symptoms in a short time,thereby worthy of promotion and application.