摘要
目的评价高危型人乳头瘤病毒(HC2-HPV-DNA)联合超薄液基细胞学(TCT)检测在宫颈癌和癌前病变筛查中的诊断价值。方法对2013年1—7月在无锡妇幼保健院宫颈门诊已进行HPV及TCT检测的患者694例进行研究,同时做病理组织学活检。结果 HC2-HPV的阳性率随着宫颈病变严重程度的增加而升高,差异有统计学意义(P<0.05),HPV与TCT联合检测时,对于宫颈上皮内瘤变(CIN)Ⅰ及以上的病变诊断的敏感性为85.41%,较单独应用显著提高。结论 HC2-HPV联合TCT检测可以提高宫颈癌和癌前病变筛查的准确性。
[ Objective] To evaluate the value of high risk human papillomavirus { HC2-HPV-DNA） and liquid-based thin-layer cy- tological test （TCT} detection in the screening of cervical cancer and precancerous lesion. [ Methods] A total of 694 patients, who received HC2-HPV-DNA and TCT detection in Wuxi MCH from January to July 2013, were recruited for study, meanwhile cervical biopsy was taken. [ Results] The positive rate of HC2-HPV-DNA increased significantly with the increasing grade of cervical lesions （P 〈 0.05）. Co-test of HC2-HPV-DNA and TCT for CIN I and above lesions had a sensitivity of 85.41%, representing a signifi- cant increase compared with single application. [ Conclusion] Co-test of HC2-HPV and TCT can improve the detection rate of cervi- cal cancer and precancerous lesion.
出处
《职业与健康》
CAS
2014年第9期1178-1179,1182,共3页
Occupation and Health
基金
无锡市卫生局面上项目(项目编号:MD201308)
